CategoryQuality , Analytical Chemistry - Courses
GMP Aspects of Analytical Quality Control including OOS results
Lecturer: Ms. Karen Ginsbury
Date: April 14, 2008
Location: Kfar Maccabiah, Ramat Gan
Course Language: Hebrew
Duration: 1 - Day Course
Hours: 09:00-17:00
Price: 1,750 NIS + VAT
Credit Points: 1
SKU: 08160
GMP Aspects of Analytical Quality Control including OOS results
 

 

Over the last five years or so, the Quality Control Laboratory  (one of the six systems in the novel FDA inspection model) has consistently featured at the top of the deficiency lists in regulatory inspections. Sample log-in, OOS results, analytical standards are just a few of the issues that lead to warning letters or inspectional observations. Our lecturer, Karen Ginsbury has won an international award for her lectures on the topic of GMP in the Laboratory. This is a chance to benefit from her world-wide experience so as to up-date and minimize the chance of adverse inspectional outcome in your laboratory.

Benefits to the Participants
  • Updates regarding the requirements in this topic
  • Understanding how to transform regulatory requirements into laboratory Standard Operating Procedures, Test Methods and Operating Instructions that are controlled documents, implemented and performed by qualified and competent analysts.
  • Implementations of insights that lead to minimizing the chance of adverse inspectional outcome
Issues to be covered
  • Regulation of QC testing: recent inspectional issues
    • GMP requirements: Europe vs USA (FDA)
    • Control of materials: reagents, analytical standards, water
    • Control of laboratory equipment: qualification, calibration and maintenance
  • The People Factor:
    • Methods validation and qualification of analysts
    • Methods development and transfer to QC
    • People and OOS results: prevention through training
    • The rights and wrongs of retesting
    • Supervisors, second signatures and their role in OOS results
  • Laboratory Documentation
    • Regulatory requirements
    • FDA Guide to QC laboratories
    • Qualification of pharmcopoeial methods
    • Sample receipt
    • Notebooks: manual / electronic / LIMs
    • CAPA in the laboratory
Who should attend

This course is suitable for any person involved in Quality Control, Quality Assurance, Methods development intended for transfer to QC, methods validation and any other function in the company that interacts on a regular basis with the Quality Control Laboratory.

About the Speaker
Karen Ginsbury, B.Pharm, M.Sc, MRPharmS, has over twenty years of experience in the pharmaceutical industry.  With a Bachelor of Pharmacy degree from the University of London (“The Square”) and a Master of Science in Microbiology from Birkbeck College, University of London, Karen started off with a well-rounded foundation in the basic skills appropriate to the pharmaceutical industry.  She has worked in industry for most of her career, initially in Research and Development at Smith and Nephew in England and then for seven years at Teva Pharmaceutical Industries, today the world’s largest generic manufacturer.  After leaving Teva, Karen set up her own consultancy company, PCI Pharmaceutical Consulting Israel Ltd which has been providing services to the pharmaceutical industry worldwide for the past 14 years.  PCI regularly works with pharmaceutical, biotech and API manufacturers to assist them in resolving compliance issues with regulatory authorities, in setting up, maintaining and upgrading or improving their quality systems, performing audits at vendors, contract manufacturers, laboratories as well as helping clients successfully prepare for FDA, Health Canada, EU and local regulatory inspections.
Karen was responsible for setting up the compliance department at Teva and published a book on compliance auditing, still available in the USA, that was purchased by most of the multi-national pharmaceutical companies as well as by the US FDA.
Karen regularly lectures around the world on quality topics and is renowned for her lively and engaging style of presentation.  She was winner of the Institute of Validation Technology’s “Presentation of the Year Award” in 2006 and their “Webseminar of the Year Award” in 2007.
Karen is also an active volunteer in the Parenteral Drug Association (PDA) and is currently co-editing their Technical Report on GMPs for Investigational Products.

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