12/06/2013 4 - Day Course Advanced HPLC Lecturer: Mr. Igal Gozlan

29/07/2013 2 - Day Course PAT, NIR and QBD Lecturer: Dr. Mark Howard, USA   Advanced Course

07/10/2013 3 - Day Course Analytical Chemistry in the Pharmaceutical Raw Material Laboratory Lecturer: Dr. Rivka Goldik

09/10/2013 1 - Day Course Application OF ICP-AES Inductively Coupled Plasma Atomic Emission & ICP-MS Mass Spectrometry Lecturer: Dr. Joe Brenner

28/10/2013 1 - Day Course Process Analytical Technology – PAT (Beginners) Lecturer: Dr. Yehuda Shekel

04/11/2013 3 - Day Course Troubleshooting and Solving Problems in HPLC - Advanced Lecturer: Dr. Shulamit Levin   Especially the experienced chemists might find be surprised

19/11/2013 2 - Day Course Validation of Analytical Methods Lecturer: Dr. Hagit Yariv

18/12/2013 2 - Day Course Formulation for Chemists Lecturer: Dr. Malcolm Ross, Switzerland

TBA 2 - Day Course Identification of Endogenous Compounds and Natural Products using LC–MS–MS Technologies Lecturer: Dr. Wilfried Niessen, The Netherlands

TBA 2 - Day Course Identification of Drug Metabolites using LC–MS–MS Technologies Lecturer: Dr. Wilfried Niessen, The Netherlands

TBA 2 - Day Course Process Scale-Up - Advanced Level Lecturer: Ariel Ewenson

TBA 2 - Day Course Retrieving Compound Identity Using LC-MS-MS Lecturer: Dr. Wilfried Niessen   This two-day course provides knowledge for structure elucidation of small molecules (drugs, pesticides, natural products, etc.) by combined liquid chromatography–tandem mass spectrometry (LC–MS–MS). We study the fragmentation of positively and negatively charged even-electron ions in MS–MS, and discuss identification strategies, both from data-acquisition and from data-processing point of view. Next to lectures and time for questions and discussion, the Course provides exercises in order to practice spectral interpretation.

TBA 3 - Day Course Sample Preparation - Introduction Lecturer: Prof. Eli Grushka

TBA 1 - Day Course Introduction to production of solid dosage forms Lecturer: Mr. Eran Yona

TBA 1 - Day Course Introduction to Solid-State NMR and its Applications for the Pharmaceutical Industry Lecturer: Prof. Robert Glaser

TBA 1 - Day Course Analytical Biotechnology: Method Development & Validation Lecturer: Prof. Ira Krull, USA

TBA 1 - Day Course Color Testing Lecturer: Dr. Yehuda Shekel

TBA 1 - Day Course Modern Thin Layer Chromatography Lecturer: Mr. Daniel Handloser

TBA 1 - Day Course Quantitative Analysis by LC–MS Lecturer: Dr. Wilfried Niessen   One of the most important applications of LC–MS is its use in routine quantitative analysis, in preclinical and clinical studies to sustain drug development, and in food safety and environmental analysis. This two-day course pays specific attention to aspects related to quantitative analysis by LC–MS for pharmaceutical applications as well as quantitative (multi)residue analysis by LC–MS for environmental and food-safety applications.

TBA 1 - Day Course Gel Isoelectric Focusing (IEF) for the Characterization of Proteins and Peptides Lecturer: Dr. Mathew I. Weisman

18/03/2013 1 - Day Course Analytical Instrument Qualification Lecturer: Ms. Karen Ginsbury

TBA 2 - Day Course Analytical Approaches and Instrumentation for Characterization of Biopharmaceuticals Lecturer: Prof. Ira Krull, USA

TBA 2 - Day Course Chemometric Techniques for Quantitative Analysis Lecturer: Dr. Richard Kramer, USA   This course is designed to get the student quickly "up to speed" with the Multiple Linear Regressions and Factor-Based techniques used to produce quantitative calibrations from instrumental and other data: Classical Least-Squares (CLS), Inverse Least-Squares (ILS), Principle Component Regression (PCR) and Partial Least-Squares in latent variables (PLS). The emphasis will be on using actual and synthetic data to gain a practical understanding of the different techniques and their proper application. This short course is normally presented over 2 days. A 1-day version is also available, but we strongly recommend that you choose the 2-day version. The short course may be supplemented by additional workshop days during which the instructor works with your people on your actual applications and data.

TBA 1 - Day Course Biopharmaceutics for NCE Oral Drug Delivery, Key Drivers & Challenges Lecturer: Dr. Dionigio Franchi, Italy

29/01/2013 1 - Day Course Workshop on Human Errors And Out-of-Specification Test Result Professional management: Dr. Ilya Kuselman

TBA 1 - Day Course Chiral Separations and Separation Mechanisms Lecturer: Prof. Nelu Grinberg, USA   The course will focus on specific interactions between the enantiomeric analytes and each specific chiral stationary phase, rather than the techniques used to separate enantiomers. This approach will allow the participants to understand the strategies for development of a separation of enantiomers, along with the conditions to achieve each type of interaction.

TBA 1 - Day Course Analytical Development in Generic Pharma Lecturer: Dr. Vladimir Yoffe

TBA 2 - Day Course Formulation and Analytical Aspects of Oral Modified Release Products Lecturer: Dr. Malcolm Ross, Switzerland

12/12/2012 2 - Day Course Dissolution Testing Lecturer: Dr. Malcolm Ross, Switzerland   The course looks at the history of the dissolution test in order to understand how we have arrived at today’s situation. It will review the test methods, both official and unofficial and discuss the development and validation of dissolution tests.

27/11/2012 3 - Day Course HPLC Method Development Lecturers: Prof. Eli Grushka, Dr. Igal Bar-Ilan

06/08/2012 1 - Day Course Protein Purification and Characterization by pH Gradient Elution Ion Exchange Chromatography (IEC) Lecturer: Dr. Mathew I. Weisman

TBA 2 - Day Course Formulation for Chemists Lecturer: Dr. Malcolm Ross, Switzerland

11/07/2012 2 - Day Course Quantitative Analysis by LC–MS Lecturer: Dr. Wilfried Niessen   One of the most important applications of LC–MS is its use in routine quantitative analysis, in preclinical and clinical studies to sustain drug development, and in food safety and environmental analysis. This two-day course pays specific attention to aspects related to quantitative analysis by LC–MS for pharmaceutical applications as well as quantitative (multi)residue analysis by LC–MS for environmental and food-safety applications.

03/07/2012 1 - Day Course Gel Isoelectric Focusing (IEF) for the Characterization of Proteins and Peptides Lecturer: Dr. Mathew I. Weisman   The course will describe basic principles and practical aspects of the electrophoretic technique of gel isoelectric focusing (IEF) in the characterization of proteins and how the technique can be fully exploited in the characterization of biopharmaceutical products (protein and peptide pharmaceuticals) for presentation to regulatory authorities.

19/06/2012 2 Meetings Introduction to Protein Purification Lecturer: Dr. Mario Lebendiker

14/05/2012 1 - Day Course Modern Thin Layer Chromatography Lecturer: Mr. Daniel Handloser, Switzerland, Guest Speaker: Dr. Mehmet Dogan, Turkey   The course is designed to give a theoretical overview and a practical introduction to the possibilities of modern HPTLC.

30/04/2012 1 - Day Course Application OF ICP-AES Inductively Coupled Plasma Atomic Emission & ICP-MS Mass Spectrometry Lecturer: Dr. Joe Brenner

22/02/2012 3 - Day Course Analytical Chemistry in the Pharmaceutical Raw Material Laboratory Lecturer: Dr. Rivka Goldik   The purpose of this seminar is to deepen the knowledge and awareness of the tests performed in the raw material laboratory and to increase the ability of performance and the product's quality, as well as to decrease misleading and to obtain the ability to predict and solve problems.

14/02/2012 3 - Day Course Troubleshooting and Solving Problems in HPLC - Advanced Lecturer: Dr. Shulamit Levin   Especially the experienced chemists might find be surprised

TBA 1 - Day Course Proteins - Validation of Analytical Methods Lecturer: Prof. Ira Krull, USA   The course will provide a description and summary of how to develop, optimize, and validate analytical methods for small and large biomolecules. The course will pursue commonly found protein variants and posttranslational modifications in biopharmaceutical products, and how these are commonly assayed for today. Current FDA requirements for protein biopharmaceutical products will also be explored and intensively discussed.

10/01/2012 1 - Day Course Analytical Methods in Biotechnology Lecturer: Prof. Ira Krull   Separation Techniques & Instrumentation Involved in the Biotech Industry

02/01/2012 2 - Day Course Validation of Analytical Methods Lecturer: Dr. Hagit Yariv

TBA 2 - Day Course Preparative High Performance Liquid Chromatography Lecturer: Dr. Henri Colin   This course is intended for production managers, chemical engineers and chemists in the pharmaceutical industry who want to understand the principles of PHPLC and some of its key features for successful applications at pilot and production levels.

TBA 2 - Day Course Developing methods of isolation and identification Lecturer: Mr. Igal Gozlan

TBA 2 - Day Course Strategies and Methods for Investigating and Controlling Impurities in Pharmaceuticals Lecturer: Dr. Bernard A. Olsen, USA

TBA 3 - Day Course Bio-chemometrics: Elementary statistics Lecturer: Dr. Evgeny Tartakovsky   This three-day course presents in a systematic manner the basic principles of chemometrics in the context of bio-analytical, analytical chemistry as well as of R&D activities. The course comprises a large number of real-life examples and exercises.

05/07/2011 1 - Day Course Pharmaceutical Polymers Lecturer: Dr. Adel Penhasi

05/07/2011 1 - Day Course Enhancing QC Laboratory Efficiency, a Course for Managers Lecturer: Dr. Sigalit Arieli-Portnoy

27/06/2011 1 - Day Course Analytical Development in Generic Pharma Lecturer: Dr. Vladimir Yoffe

10/02/2011 1 - Day Course Chiral Recognition and Separation Mechanisms Lecturer: Prof. Nelu Grinberg, USA   The course will focus on specific interactions between the enantiomeric analytes and each specific chiral stationary phase, rather than the techniques used to separate enantiomers. This approach will allow the participants to understand the strategies for development of a separation of enantiomers, along with the conditions to achieve each type of interaction.

09/02/2011 1 - Day Course Biophamaceutics for Chemists - Concepts and Applications Lecturer: Dr. Dionigio Franchi, Italy

09/02/2011 1 - Day Course Developing Structured, Robust and Repeatable Scale-up Processes :

08/02/2011 1 - Day Course On-line Control and Supervision Along the Supply Chain :

07/02/2011 1 - Day Course Developing Efficient Communication Between QC Labs and Production Staff Lecturer: Dr. Sigalit Arieli-Portnoy

19/12/2010 2 - Day Course Dissolution Testing Lecturer: Dr. Malcolm Ross, Switzerland   The course looks at the history of the dissolution test in order to understand how we have arrived at today’s situation. It will review the test methods, both official and unofficial and discuss the development and validation of dissolution tests.

16/11/2010 3 - Day Course Stabilization of Proteins and Peptides along the Formulation Process Lecturer: Dr. Mark Cornell Manning, USA

09/11/2010 3 - Day Course HPLC Method Development Lecturers: Prof. Eli Grushka, Dr. Igal Bar-Ilan

12/10/2010 1 - Day Course Process Analytical Technology – PAT (Beginners) Lecturer: Dr. Yehuda Shekel

14/09/2010 1 - Day Course Color Testing Lecturer: Dr. Yehuda Shekel

12/09/2010 2 - Day Course Retrieving Compound Identity Using LC-MS-MS Lecturer: Dr. Wilfried Niessen   This two-day course provides knowledge for structure elucidation of small molecules (drugs, pesticides, natural products, etc.) by combined liquid chromatography–tandem mass spectrometry (LC–MS–MS). We study the fragmentation of positively and negatively charged even-electron ions in MS–MS, and discuss identification strategies, both from data-acquisition and from data-processing point of view. Next to lectures and time for questions and discussion, the Course provides exercises in order to practice spectral interpretation.

07/07/2010 1 - Day Course Quality Assurance in the QC Laboratory Lecturer: Ms. Karen Ginsbury

02/06/2010 3 - Day Course Troubleshooting and Solving Problems in HPLC - Advanced Lecturer: Dr. Shulamit Levin   Especially the experienced chemists might find be surprised

03/05/2010 2 - Day Course Validation of Analytical Methods Lecturer: Dr. Hagit Yariv

26/04/2010 1 - Day Course Atomic Absorption – AA Lecturer: Dr. Yaakov Tabak

TBA 1 - Day Course Analytical Instrument Qualification Lecturer: Ms. Karen Ginsbury   This one day seminar will review the USP Chapter on Analytical Instrument Qualification (AIQ) in the perspective of regulatory requirements (EU and FDA), guidance and expectations.

21/03/2010 2 - Day Course Formulation for Chemists Lecturer: Dr. Malcolm Ross, Switzerland

04/03/2010 4 - Day Course Advanced HPLC Lecturer: Mr. Igal Gozlan

24/02/2010 1 - Day Course Enhancing Laboratory Efficiency , a Course for Managers Lecturer: Dr. Sigalit Arieli-Portnoy

21/01/2010 1 - Day Course CITAC Workshop Lecturers: Dr.I.Kuselman, Dr. W.Koch, Prof.H.Emons, Prof.I.Leito, Prof. P.De Bievre, Dr. J.Messman   The course will cover metrological principles and practice in analytical laboratories important for quality assurance of analytical results, required by GLP & GMP standards, ISO/IEC 17025 standard, spread for competence of testing laboratories, other international documents and regulations. Use of reference materials as measurement standards, calculation of measurement uncertainty of analytical results, traceability of a routine result to national and international measurement standards and System International of Units (SI), interlaboratory comparisons and proficiency testing are the topics of the course.

17/01/2010 1/2 - Day Course Gel Permeation Chromatrography (GPC) Systems in Pharmaceutical Applications Lecturer: Dr. Mark Pothecary, UK

10/09/2009 1 - Day Course GMP Aspects of Analytical Quality Control including OOS results Lecturer: Ms. Karen Ginsbury   The Quality Control Laboratory is consistently featuring at the top of the deficiency lists in regulatory inspections. This is a chance to be up-dated and to minimize the chance of adverse inspectional outcome in your laboratory.

TBA 1 - Day Course QC Managers Forum : Dr. Orna Dreazen

TBA 2 - Day Course Validation of Analytical Methods Lecturer: Dr. Hagit Yariv

17/06/2009 1 - Day Course Modern Thin Layer Chromatography Lecturer: Mr. Daniel Handloser, Switzerland   The course is designed to give a theoretical overview and a practical introduction to the possibilities of modern HPTLC.

TBA 2 - Day Course Process Scale-Up - Advanced Level Lecturer: Ariel Ewenson, Ph.D

12/05/2009 1 - Day Course Validation of Analytical Methods for Proteins Lecturer: Prof. Ira Krull, USA   The course will provide a description and summary of how to develop, optimize, and validate analytical methods for small and large biomolecules. The course will pursue commonly found protein variants and posttranslational modifications in biopharmaceutical products, and how these are commonly assayed for today. Current FDA requirements for protein biopharmaceutical products will also be explored and intensively discussed.

24/02/2009 4 Meetings Introduction to Scale-Up :

27/01/2009 1 - Day Course Particle & Material Characterization :   The one day seminar will provide a basic and practical overview of Particle size and distribution, shape, rheology, dispersion stability and how these various material properties can be linked together and used in conjunction with each other for enhanced product understanding.

22/01/2009 1 - Day Course Chiral Recognition and Separation Mechanisms Lecturer: Prof. Nelu Grinberg, USA   The course will focus on specific interactions between the enantiomeric analytes and each specific chiral stationary phase, rather than the techniques used to separate enantiomers. This approach will allow the participants to understand the strategies for development of a separation of enantiomers, along with the conditions to achieve each type of interaction.

TBA 1 - Day Course Theory, Fundamentals, Methods and Applications of Omics Technologies – Proteomics, Peptidomics, Glycomics, Metabolomics and Other Omics Lecturer: Prof. Ira Krull   This course will provide a description and summary of various omics approaches in practice today in the pharmaceutical, chemical, biological, biotechnological, and life sciences areas. These scientific fields of study include ones such as: proteomics, peptidomics, metabolomics, glycomics and other omics for both small and large molecules and their interactions.

06/08/2008 1 - Day Course Analytical Instrument Qualification - AIQ Lecturer: Ms. Karen Ginsbury   This one day seminar will review the USP Chapter on Analytical Instrument Qualification (AIQ) in the perspective of regulatory requirements (EU and FDA), guidance and expectations.

11/06/2008 1 - Day Course Validation of Analytical Methods Lecturer: Dr. Hagit Yariv

14/04/2008 1 - Day Course GMP Aspects of Analytical Quality Control including OOS results Lecturer: Ms. Karen Ginsbury   The Quality Control Laboratory is consistently featuring at the top of the deficiency lists in regulatory inspections. This is a chance to be up-dated and to minimize the chance of adverse inspectional outcome in your laboratory.

TBA 2 - Day Course Analyzing Biological Assays Lecturer: Dr. John Dunn (USA)   The course covers nonlinear curve fitting, parallelism and other computations as they relate to bioassay optimization and analysis, and a comprehensive method for evaluating and troubleshooting failed reagents and incubation conditions.

17/12/2007 2 - Day Course DISSOLUTION TESTING Lecturer: Dr. Malcolm Ross, Switzerland

21/11/2007 1 - Day Course QC Lab Management Lecturers: Amit Lahav, Larisa Amir, Dr. Orna Dreazen, Ruth Huberman, Mr. Teddy Hoffman

29/10/2007 2 - Day Course Development and Validation of Bioassays Lecturer: Dr. Ana Menendez, USA   The lecture portion of this course will outline sensible approaches to develop reproducible bioassays using live systems and/or biologically derived reagents. These approaches will be supplemented by guidelines to meet regulatory requirements according to their application. In addition, a workshop on writing validation protocols will provide hands-on experience to cover this pivotal document. During the course students will also hear caser studies that will add relevance to the lecture materials and provide a launch point for class discussion.

25/07/2007 2 - Day Course Analytical Biotechnology Lecturer: Prof. Ira Krull   Separation Techniques & Instrumentation Involved in the Biotech Industry

29/05/2007 2 - Day Course Proteins & Related Materials Lecturer: Prof. Ira Krull

28/05/2007 1 - Day Course Polymorphism in the Pharmaceutical Industry Lecturer: Dr. Judith Aronhime

20/03/2007 1 - Day Course Thin Layer Chromatography (TLC) Lecturer: Mr. Daniel Handloser, Switzerland   The course is designed to provide analysts with theoretical foundation of and practical experience with modern TLC. Participants will learn to use state-of-the-art instrumentation to develop, optimize, validate and apply methods for qualitative and quantitative determinations.

05/02/2007 1 - Day Course Validation of Analytical Methods for Proteins Lecturer: Prof. Ira Krull   The course will provide a description and summary of how to develop, optimize, and validate analytical methods for small and large biomolecules. The course will pursue commonly found protein variants and posttranslational modifications in biopharmaceutical products, and how these are commonly assayed for today.

19/01/2006 1 - Day Course Modern HPLC Theory and Practice Lecturer: Prof. Yuri Kazakevich

15/01/2006 2 - Day Course HPLC Method Development Lecturer: Prof. Yuri Kazakevich